TNNI3 anticorps (pSer23, pSer24)

N° du produit ABIN6254118

L’anticorps Lapin Polyclonal anti-TNNI3 a été validé pour WB et ELISA. Il convient pour détecter TNNI3 dans des échantillons de Souris. Il y a 2+ publications disponibles.

Aperçu rapide pour TNNI3 anticorps (pSer23, pSer24) (ABIN6254118)

Antigène: TNNI3 (Cardiac Troponin I (TNNI3))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNNI3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TNNI3 anticorps

Épitope: pSer23, pSer24

Specificité: Specific for endogenous levels of the ~25 kDa cardiac troponin I protein phosphorylated at Ser23/24. Immunolabeling is blocked by preadsorption with the phosphopeptide used as antigen, but not by the corresponding non-phosphopeptide.

Réactivité croisée: Humain, Souris, Rat

Homologie: human, non-human primate

Attributs du produit: Our Troponin I (cardiac) Ser23/24 rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects Troponin I (cardiac) Ser23/24 and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Purification: Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.

Immunogène: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser23/24 of mouse troponin 1, cardiac (cTnI), conjugated to keyhole limpet hemocyanin (KLH).

Isotype: IgG

Information d'application

Indications d'application: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Stock: -20 °C

Stockage commentaire: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Date de péremption: 12 months

Références pour anticorps anti-TNNI3 (ABIN6254118)

Lin, Schmidt, Fritz, Jeong, Cammarato, Foster, Biesiadecki, McKinsey, Woulfe: "Site-specific acetyl-mimetic modification of cardiac troponin I modulates myofilament relaxation and calcium sensitivity." dans: Journal of molecular and cellular cardiology, Vol. 139, pp. 135-147, (2020) (PubMed).

Woulfe, Ferrara, Pioner, Mahaffey, Coppini, Scellini, Ferrantini, Piroddi, Tesi, Poggesi, Jeong: "A Novel Method of Isolating Myofibrils From Primary Cardiomyocyte Culture Suitable for Myofibril Mechanical Study." dans: Frontiers in cardiovascular medicine, Vol. 6, pp. 12, (2019) (PubMed).

Détails sur TNNI3

Antigène: TNNI3 (Cardiac Troponin I (TNNI3))

Autre désignation: TNNI3

Sujet:

Synonyms: cardiac muscle antibody, Cardiac troponin I antibody, Cardiac Troponin I antibody, cardiomyopathy dilated 2A (autosomal recessive) antibody, Cardiomyopathy familial hypertrophic 7 included antibody, CMD1FF antibody, CMD2A antibody, CMH7 antibody, cTnI antibody, Familial hypertrophic cardiomyopathy 7 antibody, MGC116817 antibody, RCM1 antibody, Tn1 antibody, Tni antibody, TNN I3 antibody, TNNC 1 antibody, TNNC1 antibody, TNNI3 antibody, TNNI3_HUMAN antibody, Troponin I antibody, Troponin I cardiac antibody, Troponin I cardiac muscle antibody, Troponin I cardiac muscle isoform antibody, Troponin I type 3 cardiac antibody, troponin I cardiac 3 antibody, TroponinI antibody, Troponin I type 3 (cardiac) antibody

Description Logic: Our Troponin I (cardiac) Ser23/24 rabbit polyclonal phosphospecific primary antibody is produced . It detects Troponin I (cardiac) Ser23/24 and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Gene Name Alternatives: TNNI3

Poids moléculaire: 25 kDa

ID gène: 21954

UniProt: P48787